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Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells.


ABSTRACT: The present data describe the relative neuro-2a cellular differentiation induced by reducing serum concentration (0.1% FBS) in DMEM in the presence/absence of 20??M retinoic acid (RA). Neurite outgrowth was observed within 24?h in DMEM supplemented with reduced serum and retinoic acid (GpIV). The CFSE based proliferation assay data signified cessation of neuro-2a cellular proliferation in GpIV. An increase in the number of cells arrested at G0/G1 phase was also evident in GpIV and DMEM supplemented with 0.1% FBS (GpIII). Moreover, GpIV cells had improved mRNA and protein expression of Rbfox3/NeuN and choline acetyltransferase (ChAT).

SUBMITTER: Kumar M 

PROVIDER: S-EPMC6282191 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Data on retinoic acid and reduced serum concentration induced differentiation of Neuro-2a neuroblastoma cells.

Kumar Mukesh M   Katyal Anju A  

Data in brief 20181123


The present data describe the relative neuro-2a cellular differentiation induced by reducing serum concentration (0.1% FBS) in DMEM in the presence/absence of 20 μM retinoic acid (RA). Neurite outgrowth was observed within 24 h in DMEM supplemented with reduced serum and retinoic acid (GpIV). The CFSE based proliferation assay data signified cessation of neuro-2a cellular proliferation in GpIV. An increase in the number of cells arrested at G<sub>0</sub>/G<sub>1</sub> phase was also evident in G  ...[more]

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