Early predictors of mortality in parkinsonism and Parkinson disease: A population-based study.

ABSTRACT:

Objective

To examine mortality and associated risk factors, including possible effects of mild cognitive impairment, imaging, and CSF abnormalities, in a community-based population with incident parkinsonism and Parkinson disease.

Methods

One hundred eighty-two patients with new-onset, idiopathic parkinsonism were diagnosed from January 2004 through April 2009, in a catchment area of 142,000 inhabitants in Sweden. Patients were comprehensively investigated according to a multimodal research protocol and followed prospectively for up to 13.5 years. A total of 109 patients died. Mortality rates in the general Swedish population were used to calculate standardized mortality ratio and expected survival, and Cox proportional hazard models were used to investigate independent pred

SUBMITTER: Backstrom D 

PROVIDER: S-EPMC6282235 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature