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Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression.

ABSTRACT: The data set presented here is associated with the article "Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes" (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1?µM). It also shows NF-?B p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5-1.5% oxygen in the presence and absence of BAPTA-AM or the NF-?B inhibitor SN50 for 48?h prior to RNA isolation and PCR analysis.

SUBMITTER: Al-Anazi A

PROVIDER: S-EPMC6282628 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression.

Al-Anazi Azizah A Parhar Ranjit R Saleh Soad S Al-Hijailan Reem R Inglis Angela A Al-Jufan Mansour M Bazzi Mohammed M Hashmi Sarwar S Conca Walter W Collison Kate K Al-Mohanna Futwan F

Data in brief 20181101

The data set presented here is associated with the article "Intracellular calcium and NF-<sub>k</sub>B regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes" (Al-Anazi et al., 2018). Data illustrate hypoxia-induced VEGF and leptin expression in human adipocytes treated with the calcium chelator BAPTA-AM (1 µM). It also shows NF-κB p65 induced expression by hypoxia. Preadipocytes were differentiated for 14 days and then subjected to 0.5-1.5% oxygen in the prese ...[more]

PMID: 30547064

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