A potential role of extended simple sequence repeats in competing endogenous RNA crosstalk.
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ABSTRACT:
SUBMITTER: Witkos TM
PROVIDER: S-EPMC6284579 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
A potential role of extended simple sequence repeats in competing endogenous RNA crosstalk.
Witkos Tomasz M TM Krzyzosiak Wlodzimierz J WJ Fiszer Agnieszka A Koscianska Edyta E
RNA biology 20181105 11
MicroRNA (miRNA)-mediated crosstalk between coding and non-coding RNAs of various types is known as the competing endogenous RNA (ceRNA) concept. Here, we propose that there is a specific variant of the ceRNA language that takes advantage of simple sequence repeat (SSR) wording. We applied bioinformatics tools to identify human transcripts that may be regarded as repeat-associated ceRNAs (raceRNAs). Multiple protein-coding transcripts, transcribed pseudogenes, long non-coding RNAs (lncRNAs) and ...[more]
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