Ontology highlight
ABSTRACT:
SUBMITTER: Lavorato M
PROVIDER: S-EPMC6288074 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Lavorato Manuela M Loro Emanuele E Debattisti Valentina V Khurana Tejvir S TS Franzini-Armstrong Clara C
Journal of cell science 20181205 23
Mitochondria respond to stress and undergo fusion and fission at variable rates, depending on cell status. To understand mitochondrial behavior during muscle fatigue, we investigated mitochondrial ultrastructure and expression levels of a fission- and stress-related protein in fast-twitch muscle fibers of mice subjected to fatigue testing. Mice were subjected to running at increasing speed until exhaustion at 45 min-1 h. In further experiments, high-intensity muscle stimulation through the sciat ...[more]