Ontology highlight
ABSTRACT:
SUBMITTER: Paley MA
PROVIDER: S-EPMC6288302 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Paley Michael A MA Karacal Humeyra H Rao P Kumar PK Margolis Todd P TP Miner Jonathan J JJ
American journal of ophthalmology case reports 20181204
<h4>Purpose</h4>To report the successful use of tofacitinib in the treatment of refractory uveitis and scleritis.<h4>Observations</h4>Two patients, one with scleritis and another with anterior and intermediate uveitis, presented with refractory disease after failure of multiple steroid-sparing therapies. Treatment with tofacitinib led to durable resolution of uveitis and scleritis.<h4>Conclusions and importance</h4>Tofacitinib is a potential novel treatment option for refractory, noninfectious i ...[more]