Can a Charged Surfactant Unfold an Uncharged Protein?
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ABSTRACT: Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.
SUBMITTER: Hojgaard C
PROVIDER: S-EPMC6289093 | biostudies-literature |
REPOSITORIES: biostudies-literature
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