Ontology highlight
ABSTRACT:
SUBMITTER: Shulzhenko N
PROVIDER: S-EPMC6289276 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Clinical immunology (Orlando, Fla.) 20180919
Common variable immunodeficiency (CVID), the most common symptomatic primary antibody deficiency, is accompanied in some patients by a duodenal inflammation and malabsorption syndrome known as CVID enteropathy (E-CVID).The goal of this study was to investigate the immunological abnormalities in CVID patients that lead to enteropathy as well as the contribution of intestinal microbiota to this process.We found that, in contrast to noE-CVID patients (without enteropathy), E-CVID patients have exce ...[more]