Ontology highlight
ABSTRACT:
SUBMITTER: Clark SM
PROVIDER: S-EPMC6289779 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Clark Sarah M SM Song Chang C Li Xin X Keegan Achsah D AD Tonelli Leonardo H LH
Cytokine 20180719
Psychological stress is known to have profound effects on immune function and to promote inflammatory conditions. Elevated circulating levels of cytokines associated with stress are known to increase the risk to several diseases, but little is known about this mechanism. This study assessed the role of T cells on cytokine levels after exposure to stress in the learned helplessness paradigm. Adoptive transfer of CD4<sup>+</sup> T cells into Rag2<sup>-/-</sup> mice did not change cytokine levels t ...[more]