Ontology highlight
ABSTRACT:
SUBMITTER: Ma HD
PROVIDER: S-EPMC6290354 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Ma Hong-Di HD Zhao Zhi-Bin ZB Ma Wen-Tao WT Liu Qing-Zhi QZ Gao Cai-Yue CY Li Liang L Wang Jinjun J Tsuneyama Koichi K Liu Bin B Zhang Weici W Zhou Yongjian Y Gershwin M Eric ME Lian Zhe-Xiong ZX
Journal of autoimmunity 20181017
Gut microbiota and bacterial translocation have been implicated as significant contributors to mucosal immune responses and tolerance; alteration of microbial molecules, termed pathogen-associated molecular patterns (PAMP) and bacterial translocation are associated with immune pathology. However, the mechanisms by which dysregulated gut microbiota promotes autoimmunity is unclear. We have taken advantage of a well-characterized murine model of primary biliary cholangitis, dnTGFβRII mice, and an ...[more]