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Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation.


ABSTRACT: Pure seminoma is a histological subtype of testicular cancer that accounts for 50% of testicular germ cell tumors. It has a very low rate of metastasis to the central nervous system, with only one previously reported case of neoplastic meningitis (cancer that has spread to the cerebrospinal fluid). Traditionally, neoplastic meningitis has an ominous prognosis when associated with primary tumors that commonly spread to the leptomeninges, like breast and lung. This article highlights a unique case of pure seminoma with neoplastic meningitis and illustrates the effectiveness of craniospinal irradiation as a treatment modality.

SUBMITTER: Sinicrope KD 

PROVIDER: S-EPMC6291321 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation.

Sinicrope Kaylyn D KD   Kaplan Alexander B AB   Brastianos Priscilla K PK  

The oncologist 20180716 11


Pure seminoma is a histological subtype of testicular cancer that accounts for 50% of testicular germ cell tumors. It has a very low rate of metastasis to the central nervous system, with only one previously reported case of neoplastic meningitis (cancer that has spread to the cerebrospinal fluid). Traditionally, neoplastic meningitis has an ominous prognosis when associated with primary tumors that commonly spread to the leptomeninges, like breast and lung. This article highlights a unique case  ...[more]

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