Ontology highlight
ABSTRACT:
SUBMITTER: Tatangelo F
PROVIDER: S-EPMC6292169 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Tatangelo Fabiana F Di Mauro Annabella A Scognamiglio Giosuè G Aquino Gabriella G Lettiero Antonio A Delrio Paolo P Avallone Antonio A Cantile Monica M Botti Gerardo G
Journal of translational medicine 20181212 1
<h4>Background</h4>Increasing evidences showed that the location of the primary tumor on the right (proximal) or left (distal) side of the colon have a prognostic/predictive value for colon cancer patients. However, the understanding of the molecular mechanisms that contribute to the pathogenesis in different location of colon is still unclear. Probably an important role could be played by genes that control the spatial-temporal development of bodily structures, such as HOX genes.<h4>Methods</h4 ...[more]