Relative miRNA and mRNA expression involved in arsenic methylation.
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ABSTRACT:
SUBMITTER: Cheng H
PROVIDER: S-EPMC6292570 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Relative miRNA and mRNA expression involved in arsenic methylation.
Cheng Huirong H Hu Pei P Wen Weihua W Liu Ling L
PloS one 20181213 12
Three arsenic species in urine are measured using an atomic absorption spectrophotometer. RT-PCR is performed to detect the expression levels of AS3MT, 3 miRNAs, and 17 relative mRNAs in 43 workers producing arsenic trioxide, 36 workers who stopped exposure to arsenic for 85 days, and 24 individuals as the control group. The concentrations of urinary arsenic are very high in workers. A negative correlation between AS3MT and MiR-548c-3p is found. There exist significant changes for most selected ...[more]
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