Ontology highlight
ABSTRACT:
SUBMITTER: Allen NJ
PROVIDER: S-EPMC6292669 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Allen Nicola J NJ Lyons David A DA
Science (New York, N.Y.) 20181001 6411
Glia constitute roughly half of the cells of the central nervous system (CNS) but were long-considered to be static bystanders to its formation and function. Here we provide an overview of how the diverse and dynamic functions of glial cells orchestrate essentially all aspects of nervous system formation and function. Radial glia, astrocytes, oligodendrocyte progenitor cells, oligodendrocytes, and microglia each influence nervous system development, from neuronal birth, migration, axon specifica ...[more]