Antiseptic effect of low-concentration povidone-iodine applied with a depot device in the conjunctiva before cataract surgery.

ABSTRACT: PURPOSE:Examine the antiseptic effect of long-term low-concentration (0.3%) povidone-iodine (PI) before cataract surgery. SETTING:St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. DESIGN:Single-armed prospective clinical study. METHODS:Repeated measure of preoperative conjunctival samples from 51 participants were obtained the day before surgery (T1), the day of surgery after treatment with ophthalmic NSAID (T2), and after additional treatment with low-concentration PI (T3) given by placing a pledget soaked in a mix of eye-drops in fornix inferior for 20?min. RESULTS:Before surgery, and before any type of treatment (T1), bacterial growth (?5 BC) in the conjunctiva was identified in 36 (66.7%) of the participants. After treatment with ophthalmic NSAID (T2), and after additional treatment with low-concentration PI (T3), bacteria were identified in 31 (60.8%) and 12 (23.4%) participants, respectively. All except one of the participants with a measurable change from T2 to T3 (n?=?31, 60.8% of total sample), experienced a decrease in number of bacterial colonies (BC) after treatment with low-concentration PI (96.8 vs. 3.2%, p?

SUBMITTER: Wass S 

PROVIDER: S-EPMC6292903 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature