Ontology highlight
ABSTRACT:
SUBMITTER: Ganief N
PROVIDER: S-EPMC6292918 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Ganief Naadir N Sjouerman Jessica J Albeldas Claudia C Nakedi Kehilwe C KC Hermann Clemens C Calder Bridget B Blackburn Jonathan M JM Soares Nelson C NC
Emerging microbes & infections 20181213 1
Mycobacterium manages to evade the host cell immune system, partially owing to its ability to survive redox stress after macrophage engulfment. Exposure to redox stress has been linked to later replication, persistence, and latent infection. In this work, mass spectrometry was used to elucidate the cell-wide changes that occur in response to sublethal doses of hydrogen peroxide and nitric oxide over time, with Mycobacterium smegmatis being used as a model organism. A total of 3135 proteins were ...[more]