Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy.
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ABSTRACT:
SUBMITTER: Edridge AWD
PROVIDER: S-EPMC6293039 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
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Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy.
Edridge Arthur W D AWD Deijs Martin M Namazzi Ruth R Cristella Cosimo C Jebbink Maarten F MF Maurer Irma I Kootstra Neeltje A NA Buluma Linda R LR van Woensel Job B M JBM de Jong Menno D MD Idro Richard R Boele van Hensbroek Michael M van der Hoek Lia L
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20190101 1
A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its closest relative. The virus was named Ntwetwe virus, after the hometown of the patient. ...[more]
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