Dataset Information

Occupational exposure to metals and other elements in the tractor production.

ABSTRACT: BACKGROUND:Exposure to metals via air sampling in workplace has been extensively studied; however, the magnitude of individual exposure in various occupational groups may vary dramatically. The aim of this cross-sectional study was to ascertain exposure to selected metals from metal fumes in a series of typical workplaces of contemporary tractor production. METHODS:Ninety-eight (median age 41 (interquartile range (IQR) 23) years, all men) workers from Minsk Tractor Plant were categorized into four groups, including assembly shop workers (group 1); thermal shop staff (group 2); steelmakers (group 3) and welders (group 4). Hair samples (0.25 g) of each worker were tested for Ca, Mg, P, Cu, Fe, Zn, Al, Mn, Cr, Ni, Pb and Cd using atomic emission spectrophotometry. We then tested between-group differences of log-transformed element concentrations using analysis of variance, followed by logistic regression to determine the odds ratio (OR) with its 95% confidence interval (CI) of high exposure for four selected groups. RESULTS:The median work duration in workers was 6 (IQR 15) years, more in group 1 (10 (IQR 23)). Eight out of 12 included elements yielded significant between-group differences, including Mg, P, Fe, Zn, Mn, Cr, Ni and Cd. Steelmakers had higher Mn hair concentrations (F-ratio 10.41, p<0.001); whereas Fe (F-ratio 12.48, p<0.001), P (F-ratio 12.68, p<0.001), Zn (F-ratio 6.07, p<0.001) and Cr (F-ratio 20.54, p<0.001) were higher in welders. OR of high exposure to Mg in group 3 was 10.00 (95% CI 1.14-87.52), whereas the OR of high exposure to P in group 4 was 18.64 (95% CI 2.22-156.85) compared to group 1. CONCLUSIONS:In the modern full-cycle tractor production, welders may have higher exposure to Fe, P, Zn and Cr, as opposed to steelmakers with higher Mn hair concentrations.

SUBMITTER: Vinnikov D

PROVIDER: S-EPMC6294428 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Occupational exposure to metals and other elements in the tractor production.

Vinnikov Denis D Semizhon Sergey S Rybina Tatsyana T Zaitsev Viktor V Pleshkova Anna A Rybina Aliaksandra A

PloS one 20181214 12

<h4>Background</h4>Exposure to metals via air sampling in workplace has been extensively studied; however, the magnitude of individual exposure in various occupational groups may vary dramatically. The aim of this cross-sectional study was to ascertain exposure to selected metals from metal fumes in a series of typical workplaces of contemporary tractor production.<h4>Methods</h4>Ninety-eight (median age 41 (interquartile range (IQR) 23) years, all men) workers from Minsk Tractor Plant were cate ...[more]

PMID: 30550545

Similar Datasets

Project description:To estimate the current occupational cancer burden due to past exposures in Britain, estimates of the number of exposed workers at different levels are required, as well as risk estimates of cancer due to the exposures. This paper describes the methods and results for estimating the historical exposures. All occupational carcinogens or exposure circumstances classified by the International Agency for Research on Cancer as definite or probable human carcinogens and potentially to be found in British workplaces over the past 20-40 years were included in this study. Estimates of the number of people exposed by industrial sector were based predominantly on two sources of data, the CARcinogen EXposure (CAREX) database and the UK Labour Force Survey. Where possible, multiple and overlapping exposures were taken into account. Dose-response risk estimates were generally not available in the epidemiological literature for the cancer-exposure pairs in this study, and none of the sources available for obtaining the numbers exposed provided data by different levels of exposure. Industrial sectors were therefore assigned using expert judgement to 'higher'- and 'lower'-exposure groups based on the similarity of exposure to the population in the key epidemiological studies from which risk estimates had been selected. Estimates of historical exposure prevalence were obtained for 41 carcinogens or occupational circumstances. These include exposures to chemicals and metals, combustion products, other mixtures or groups of chemicals, mineral and biological dusts, physical agents and work patterns, as well as occupations and industries that have been associated with increased risk of cancer, but for which the causative agents are unknown. There were more than half a million workers exposed to each of six carcinogens (radon, solar radiation, crystalline silica, mineral oils, non-arsenical insecticides and 2,3,7,8-tetrachlorodibenzo-p-dioxin); other agents to which a large number of workers are exposed included benzene, diesel engine exhaust and environmental tobacco smoke. The study has highlighted several industrial sectors with large proportions of workers potentially exposed to multiple carcinogens. The relevant available data have been used to generate estimates of the prevalence of past exposure to occupational carcinogens to enable the occupational cancer burden in Britain to be estimated. These data are considered adequate for the present purpose, but new data on the prevalence and intensity of current occupational exposure to carcinogens should be collected to ensure that future policy decisions be based on reliable evidence.

Dataset Information

Occupational exposure to metals and other elements in the tractor production.

Publications

Occupational exposure to metals and other elements in the tractor production.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets