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Htsget: a protocol for securely streaming genomic data.


ABSTRACT:

Summary

Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration.

Availability and implementation

http://samtools.github.io/hts-specs/htsget.html.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Kelleher J 

PROVIDER: S-EPMC6298043 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Publications


<h4>Summary</h4>Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration.<h4>Availability and implementation</h4>http://samtools.github.io/hts-specs/htsget.  ...[more]

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