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RNAvista: a webserver to assess RNA secondary structures with non-canonical base pairs.

ABSTRACT: Motivation:In the study of 3D RNA structure, information about non-canonical interactions between nucleobases is increasingly important. Specialized databases support investigation of this issue based on experimental data, and several programs can annotate non-canonical base pairs in the RNA 3D structure. However, predicting the extended RNA secondary structure which describes both canonical and non-canonical interactions remains difficult. Results:Here, we present RNAvista that allows predicting an extended RNA secondary structure from sequence or from the list enumerating canonical base pairs only. RNAvista is implemented as a publicly available webserver with user-friendly interface. It runs on all major web browsers. Availability and implementation:http://rnavista.cs.put.poznan.pl.

SUBMITTER: Antczak M

PROVIDER: S-EPMC6298044 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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RNAvista: a webserver to assess RNA secondary structures with non-canonical base pairs.

Antczak Maciej M Zablocki Marcin M Zok Tomasz T Rybarczyk Agnieszka A Blazewicz Jacek J Szachniuk Marta M

Bioinformatics (Oxford, England) 20190101 1

<h4>Motivation</h4>In the study of 3D RNA structure, information about non-canonical interactions between nucleobases is increasingly important. Specialized databases support investigation of this issue based on experimental data, and several programs can annotate non-canonical base pairs in the RNA 3D structure. However, predicting the extended RNA secondary structure which describes both canonical and non-canonical interactions remains difficult.<h4>Results</h4>Here, we present RNAvista that a ...[more]

PMID: 29985979

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