The use of MRI-detected synovitis to determine the number of involved joints for the 2010 ACR/EULAR classification criteria for Rheumatoid Arthritis - is it of additional benefit?

ABSTRACT:

Objective

To assess the value of MRI-detected synovitis to determine the number of involved joints on the performance of the 2010-ACR/EULAR classification criteria for rheumatoid arthritis (RA).

Methods

277 patients with a clinical suspicion of RA consecutively included in the Leiden Early Arthritis Clinic (EAC)-cohort underwent 1.5T MRI of MCP-, wrist- and MTP-joints. Test characteristics of the 2010-criteria were calculated when the number of involved joints was determined with and without including MRI-detected synovitis. Two outcomes were studied: disease modifying anti-rheumatic drug (DMARD)-initiation and 1987-criteria fulfilment during the first year.

Results

At baseline, 143 patients were classified as RA. When MRI-detected synovitis was considered, 14 patient

SUBMITTER: Boer AC 

PROVIDER: S-EPMC6298578 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature