Ontology highlight
ABSTRACT:
SUBMITTER: Sun B
PROVIDER: S-EPMC6299367 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Sun Bingwei B Qin Weiting W Song Mingming M Liu Lu L Yu Yao Y Qi Xinxin X Sun Hui H
International journal of biological sciences 20181128 14
While neutrophils have dutifully performed their function in injury and infection, the recent works have found that cytotoxicity and/or cytostatic of neutrophils has also been observed in tumor. Till now the molecular players that participate in this neutrophils antitumoral effect remain unclear. In the current study, we find that neutrophils from healthy donors have potent suppression to tumor cell lines by physical contact. Importantly, these suppression activities seem to be cancer cell-speci ...[more]