Comparative effectiveness of management options for patients with small renal masses: a prospective cohort study.

ABSTRACT:

Objectives

To explore the comparative effectiveness of partial nephrectomy (PN), radical nephrectomy (RN), ablative therapies (ablation) and active surveillance (AS) for small renal masses (SRMs; tumour diameter ≤4.0 cm) in the domains of survival, renal function and quality of life (QoL) using the prospectively maintained Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry.

Patients and methods

Estimated glomerular filtration rate (eGFR) was calculated from creatinine values to determine renal function. QoL was measured using the Short Form 12 (SF-12) questionnaire. The Kaplan-Meier method and Cox proportional hazards regression were used for survival analysis. The mixed-effects model was used for renal function and QoL analysis.

Results

Of

SUBMITTER: Alam R 

PROVIDER: S-EPMC6301094 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature