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Novel easily available purine-based AIEgens with colour tunability and applications in lipid droplet imaging.

ABSTRACT: Recently, tetraphenylethene, triphenylamine and other man-made core AIE luminescent materials (AIEgens) have attracted significant scientific interest. However, the design and synthesis of natural product based, facile and color tunable AIEgens remains challenging. Herein, a novel series of AIEgens based on purine-core molecular rotors is reported, which can be facilely synthesized and shows color tunable emission. Moreover, these purine-based AIEgens exhibit lipid droplet specific properties in live cellular imaging with low background, high selectivity and excellent biocompatibility.

SUBMITTER: Shi L

PROVIDER: S-EPMC6301202 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Novel easily available purine-based AIEgens with colour tunability and applications in lipid droplet imaging.

Shi Lei L Li Kun K Li Ling-Ling LL Chen Shan-Yong SY Li Meng-Yang MY Zhou Qian Q Wang Nan N Yu Xiao-Qi XQ

Chemical science 20180919 48

Recently, tetraphenylethene, triphenylamine and other man-made core AIE luminescent materials (AIEgens) have attracted significant scientific interest. However, the design and synthesis of natural product based, facile and color tunable AIEgens remains challenging. Herein, a novel series of AIEgens based on purine-core molecular rotors is reported, which can be facilely synthesized and shows color tunable emission. Moreover, these purine-based AIEgens exhibit lipid droplet specific properties in ...[more]

PMID: 30647889

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