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Higher Viral Load of Emerging Norovirus GII.P16-GII.2 than Pandemic GII.4 and Epidemic GII.17, Hong Kong, China.

ABSTRACT: We compared viral load of emerging recombinant norovirus GII.P16-GII.2 with those for pandemic GII.Pe-GII.4 and epidemic GII.P17-GII.17 genotypes among inpatients in Hong Kong. Viral load of GII.P16-GII.2 was higher than those for other genotypes in different age groups. GII.P16-GII.2 is as replication competent as the pandemic genotype, explaining its high transmissibility and widespread circulation.

SUBMITTER: Cheung SKC

PROVIDER: S-EPMC6302574 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Higher Viral Load of Emerging Norovirus GII.P16-GII.2 than Pandemic GII.4 and Epidemic GII.17, Hong Kong, China.

Cheung Sarah K C SKC Kwok Kirsty K Zhang Lin-Yao LY Mohammad Kirran N KN Lui Grace C Y GCY Lee Nelson N Nelson E Anthony S EAS Lai Raymond W M RWM Leung Ting F TF Chan Paul K S PKS Chan Martin Chi-Wai MC

Emerging infectious diseases 20190101 1

We compared viral load of emerging recombinant norovirus GII.P16-GII.2 with those for pandemic GII.Pe-GII.4 and epidemic GII.P17-GII.17 genotypes among inpatients in Hong Kong. Viral load of GII.P16-GII.2 was higher than those for other genotypes in different age groups. GII.P16-GII.2 is as replication competent as the pandemic genotype, explaining its high transmissibility and widespread circulation. ...[more]

PMID: 30561298

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