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Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins.


ABSTRACT: We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings.

SUBMITTER: Rockstroh A 

PROVIDER: S-EPMC6302594 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings. ...[more]

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