Ontology highlight
ABSTRACT:
SUBMITTER: Ma TK
PROVIDER: S-EPMC6303087 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20181022 21
(+)-Hongoquercin A and B were synthesized from commercially available trans, trans-farnesol in six and eleven steps, respectively, using dual biomimetic strategies with polyketide aromatization and subsequent polyene functionalization from a common farnesyl-resorcylate intermediate. Key steps involve Pd(0)-catalyzed decarboxylative allylic rearrangement of a dioxinone β,δ-diketo ester to a β,δ-diketo dioxinone, which was readily aromatized into the corresponding resorcylate, and subsequent polye ...[more]