Ontology highlight
ABSTRACT:
SUBMITTER: Pinsent A
PROVIDER: S-EPMC6303365 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Pinsent Amy A Solomon Anthony W AW Bailey Robin L RL Bid Rhiannon R Cama Anaseini A Dean Deborah D Goodhew Brook B Gwyn Sarah E SE Jack Kelvin R KR Kandel Ram Prasad RP Kama Mike M Massae Patrick P Macleod Colin C Mabey David C W DCW Migchelsen Stephanie S Müller Andreas A Sandi Frank F Sokana Oliver O Taoaba Raebwebwe R Tekeraoi Rabebe R Martin Diana L DL White Michael T MT
Nature communications 20181221 1
Robust surveillance methods are needed for trachoma control and recrudescence monitoring, but existing methods have limitations. Here, we analyse data from nine trachoma-endemic populations and provide operational thresholds for interpretation of serological data in low-transmission and post-elimination settings. Analyses with sero-catalytic and antibody acquisition models provide insights into transmission history within each population. To accurately estimate sero-conversion rates (SCR) for tr ...[more]