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Brushfield spots and Wolfflin nodules unveiled in dark irides using near-infrared light.

ABSTRACT: Wölfflin nodules and Brushfield spots were described essentially in light colored irides. The purpose of our study is to determine if these iris features are also present in dark irides, hidden by melanin granules of the anterior leaf of the iris. We examined iris images, taken with standard visible white, as well as with near-infrared light of children with Down syndrome and without. Using white light, Brushfield spots were seen in 21% of children with Down syndrome, and Wölfflin nodules in 12% of controls (p?

SUBMITTER: Postolache L

PROVIDER: S-EPMC6303377 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Brushfield spots and Wölfflin nodules unveiled in dark irides using near-infrared light.

Postolache Lavinia L Parsa Cameron F CF

Scientific reports 20181221 1

Wölfflin nodules and Brushfield spots were described essentially in light colored irides. The purpose of our study is to determine if these iris features are also present in dark irides, hidden by melanin granules of the anterior leaf of the iris. We examined iris images, taken with standard visible white, as well as with near-infrared light of children with Down syndrome and without. Using white light, Brushfield spots were seen in 21% of children with Down syndrome, and Wölfflin nodules in 12% ...[more]

PMID: 30575783

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