Unknown

Dataset Information

0

Proposed response assessment and endpoints for meningioma clinical trials: report from the Response Assessment in Neuro-Oncology Working Group.

ABSTRACT: No standard criteria exist for assessing response and progression in clinical trials involving patients with meningioma, and there is no consensus on the optimal endpoints for trials currently under way. As a result, there is substantial variation in the design and response criteria of meningioma trials, making comparison between trials difficult. In addition, future trials should be designed with accepted standardized endpoints. The Response Assessment in Neuro-Oncology Meningioma Working Group is an international effort to develop standardized radiologic criteria for treatment response for meningioma clinical trials. In this proposal, we present the recommendations for response criteria and endpoints for clinical trials involving patients with meningiomas.

SUBMITTER: Huang RY 

PROVIDER: S-EPMC6303427 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

No standard criteria exist for assessing response and progression in clinical trials involving patients with meningioma, and there is no consensus on the optimal endpoints for trials currently under way. As a result, there is substantial variation in the design and response criteria of meningioma trials, making comparison between trials difficult. In addition, future trials should be designed with accepted standardized endpoints. The Response Assessment in Neuro-Oncology Meningioma Working Group  ...[more]

Similar Datasets

Unknown Immunotherapy response assessment in neuro-oncology: a report of the RANO working group.
| S-EPMC4638131 | biostudies-literature
Unknown Population description and clinical response assessment for spinal metastases: part 2 of the SPIne response assessment in Neuro-Oncology (SPINO) group report.
| S-EPMC6071663 | biostudies-literature
Unknown Proposed definition of competencies for surgical neuro-oncology training.
| S-EPMC8131302 | biostudies-literature
Unknown The FDA NIH Biomarkers, EndpointS, and other Tools (BEST) resource in neuro-oncology.
| S-EPMC6071649 | biostudies-literature
Unknown Comment on "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee".
| S-EPMC5761580 | biostudies-literature
Unknown Current studies and future directions for medulloblastoma: A review from the pacific pediatric neuro-oncology consortium (PNOC) disease working group.
| S-EPMC9755363 | biostudies-literature
Unknown Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology.
| S-EPMC10232854 | biostudies-literature
Unknown Proposed Standardized Neurological Endpoints for Cardiovascular Clinical Trials: An Academic Research Consortium Initiative.
| S-EPMC6251670 | biostudies-literature
Unknown Current drug development and trial designs in neuro-oncology: report from the first American Society of Clinical Oncology and Society for Neuro-Oncology Clinical Trials Conference.
| S-EPMC10401610 | biostudies-literature
Unknown Clinical Trials with Biologic Primary Endpoints in Immuno-oncology: Concepts and Usage.
| S-EPMC8738124 | biostudies-literature