Ontology highlight
ABSTRACT:
SUBMITTER: Soldatos TG
PROVIDER: S-EPMC6306940 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Soldatos Theodoros G TG Taglang Guillaume G Jackson David B DB
High-throughput 20181123 4
We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes. Building on the fact that drugs perturb the function of targets/genes, we integrated data from 8.2 million clinical reports detailing drug-induced side effects with the molecular world of drug-target information. Using this dataset, we extracted 1.8 million associations of clinical phenotypes to 770 human drug-targets. This collection is perhaps the largest phenotypic profiling reference of ...[more]