Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC6307776 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Zhang Zengjie Z Lin Jialiang J Tian Naifeng N Wu Yaosen Y Zhou Yifei Y Wang Chenggui C Wang Qingqing Q Jin Haiming H Chen Tingting T Nisar Majid M Zheng Gang G Xu Tianzhen T Gao Weiyang W Zhang Xiaolei X Wang Xiangyang X
Journal of cellular and molecular medicine 20181024 1
Melatonin is reportedly associated with intervertebral disc degeneration (IDD). Endplate cartilage is vitally important to intervertebral discs in physiological and pathological conditions. However, the effects and mechanism of melatonin on endplate chondrocytes (EPCs) are still unclear. Herein, we studied the effects of melatonin on EPC apoptosis and calcification and elucidated the underlying mechanism. Our study revealed that melatonin treatment decreases the incidence of apoptosis and inhibi ...[more]