Ontology highlight
ABSTRACT:
SUBMITTER: Atukorale PU
PROVIDER: S-EPMC6309694 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Atukorale Prabhani U PU Yang Yu-Sang YS Bekdemir Ahmet A Carney Randy P RP Silva Paulo J PJ Watson Nicki N Stellacci Francesco F Irvine Darrell J DJ
Nanoscale 20150701 26
Erythrocytes are attractive as potential cell-based drug carriers because of their abundance and long lifespan in vivo. Existing methods for loading drug cargos into erythrocytes include hypotonic treatments, electroporation, and covalent attachment onto the membrane, all of which require ex vivo manipulation. Here, we characterized the properties of amphiphilic gold nanoparticles (amph-AuNPs), comprised of a ∼2.3 nm gold core and an amphiphilic ligand shell, which are able to embed spontaneousl ...[more]