Ontology highlight
ABSTRACT:
SUBMITTER: Dewey JB
PROVIDER: S-EPMC6309882 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Dewey James B JB Xia Anping A Müller Ulrich U Belyantseva Inna A IA Applegate Brian E BE Oghalai John S JS
Cell reports 20180601 10
The stereociliary bundles of cochlear hair cells convert mechanical vibrations into the electrical signals required for auditory sensation. While the stiffness of the bundles strongly influences mechanotransduction, its influence on the vibratory response of the cochlear partition is unclear. To assess this, we measured cochlear vibrations in mutant mice with reduced bundle stiffness or with a tectorial membrane (TM) that is detached from the sensory epithelium. We found that reducing bundle sti ...[more]