Ontology highlight
ABSTRACT:
SUBMITTER: Kim J
PROVIDER: S-EPMC6311917 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Kim Jihyun J Kim June Hyuk JH Kang Hyun Guy HG Park Seog Yun SY Yu Jung Yeon JY Lee Eun Young EY Oh Sung Eun SE Kim Young Ho YH Yun Tak T Park Charny C Cho Soo Young SY You Hye Jin HJ
BMC medical genetics 20181231 Suppl 1
<h4>Background</h4>Several studies have investigated the molecular drivers and therapeutic targets in adult soft tissue sarcomas. However, such studies are limited by the genomic heterogeneity and rarity of sarcomas, particularly in those with complex and unbalanced karyotypes. Additional biomarkers are needed across sarcoma types to improve therapeutic strategies. To investigate the molecular characteristics of complex karyotype sarcomas (CKSs) for therapeutic targets, we performed genomic prof ...[more]