Ontology highlight
ABSTRACT:
SUBMITTER: Chang AY
PROVIDER: S-EPMC6313749 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Chang Aileen Y AY Tritsch Sarah S Reid St Patrick SP Martins Karen K Encinales Liliana L Pacheco Nelly N Amdur Richard L RL Porras-Ramirez Alexandra A Rico-Mendoza Alejandro A Li Guangzhao G Peng Jin J Firestein Gary S GS Simon Gary L GL Bethony Jeff M JM
Diseases (Basel, Switzerland) 20181020 4
The cytokine profile during acute chikungunya infection that predicts future chronic arthritis has not yet been investigated. We conducted a nested case-control study comparing serum cytokine concentrations during acute chikungunya infection in cases (<i>n</i> = 121) that reported the presence of chronic joint pain versus age- and gender-matched controls (<i>n</i> = 121) who reported recovery at 20 months post infection. We observed that a robust cytokine response during acute infection was corr ...[more]