Ontology highlight
ABSTRACT:
SUBMITTER: Martin Lluesma S
PROVIDER: S-EPMC6313858 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Martin Lluesma Silvia S Graciotti Michele M Chiang Cheryl Lai-Lai CL Kandalaft Lana E LE
Vaccines 20181123 4
Although different types of therapeutic vaccines against established cancerous lesions in various indications have been developed since the 1990s, their clinical benefit is still very limited. This observed lack of effectiveness in cancer eradication may be partially due to the often deficient immunocompetent status of cancer patients, which may facilitate tumor development by different mechanisms, including immune evasion. The most frequently used cellular vehicle in clinical trials are dendrit ...[more]