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Fast Tracks and Roadblocks for Zika Vaccines.

ABSTRACT: In early 2014, a relatively obscure virus, the Zika virus, made headlines worldwide following an increase in the number of congenital malformations. Since then, research on Zika virus, treatment and vaccines have progressed swiftly with various drugs being repurposed and vaccines heading into clinical trials. Nonetheless, the need for a vaccine is crucial in order to eradicate this re-emerging arthropod-borne virus which remained silent since its first discovery in 1947. In this review, we focused on how the inconspicuous virus managed to spread, the key immunological factors required for a vaccine and the various vaccine platforms that are currently being studied.

SUBMITTER: Ghaffar KA

PROVIDER: S-EPMC6313897 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Fast Tracks and Roadblocks for Zika Vaccines.

Ghaffar Khairunnisa Abdul KA Ng Lisa F P LFP Renia Laurent L

Vaccines 20181121 4

In early 2014, a relatively obscure virus, the Zika virus, made headlines worldwide following an increase in the number of congenital malformations. Since then, research on Zika virus, treatment and vaccines have progressed swiftly with various drugs being repurposed and vaccines heading into clinical trials. Nonetheless, the need for a vaccine is crucial in order to eradicate this re-emerging arthropod-borne virus which remained silent since its first discovery in 1947. In this review, we focus ...[more]

PMID: 30469444

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