Ontology highlight
ABSTRACT:
SUBMITTER: Kenney SP
PROVIDER: S-EPMC6314074 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Kenney Scott P SP Meng Xiang-Jin XJ
Cold Spring Harbor perspectives in medicine 20190102 1
Hepatitis E virus (HEV) possesses many of the features of other positive-stranded RNA viruses but also adds HEV-specific nuances, making its virus-host interactions unique. Slow virus replication kinetics and fastidious growth conditions, coupled with the historical lack of an efficient cell culture system to propagate the virus, have left many gaps in our understanding of its structure and replication cycle. Recent advances in culturing selected strains of HEV and resolving the 3D structure of ...[more]