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ABSTRACT:
SUBMITTER: Nishimura K
PROVIDER: S-EPMC6314543 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Nishimura Kohei K Komiya Masataka M Hori Tetsuya T Itoh Takehiko T Fukagawa Tatsuo T
The Journal of cell biology 20181105 1
The centromere is an important genomic locus for chromosomal segregation. Although the centromere is specified by sequence-independent epigenetic mechanisms in most organisms, it is usually composed of highly repetitive sequences, which associate with heterochromatin. We have previously generated various chicken DT40 cell lines containing differently positioned neocentromeres, which do not contain repetitive sequences and do not associate with heterochromatin. In this study, we performed systema ...[more]