Ontology highlight
ABSTRACT:
SUBMITTER: Lafaro KJ
PROVIDER: S-EPMC6315325 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Lafaro Kelly J KJ Melstrom Laleh G LG
The American journal of pathology 20190101 1
Pancreatic ductal adenocarcinoma (PDAC) is increasing in incidence and is projected to become the second leading cause of cancer death in the United States. Despite significant advances in understanding the disease, there has been minimal increase in PDAC patient survival. PDAC tumors are unique in the fact that there is significant desmoplasia. This generates a large stromal compartment composed of immune cells, inflammatory cells, growth factors, extracellular matrix, and fibroblasts, comprisi ...[more]