Dataset Information

Diversity and Ecology of Marine Algicolous Arthrinium Species as a Source of Bioactive Natural Products.

ABSTRACT: In our previous study, all Arthrinium isolates from Sargassum sp. showed high bioactivities, but studies on marine Arthrinium spp. are insufficient. In this study, a phylogenetic analysis of 28 Arthrinium isolates from seaweeds and egg masses of Arctoscopus japonicus was conducted using internal transcribed spacers, nuclear large subunit rDNA, ?-tubulin, and translation elongation factor region sequences, and their bioactivities were investigated. They were analyzed as 15 species, and 11 of them were found to be new species. Most of the extracts exhibited radical-scavenging activity, and some showed antifungal activities, tyrosinase inhibition, and quorum sensing inhibition. It was implied that marine algicolous Arthrinium spp. support the regulation of reactive oxygen species in symbiotic algae and protect against pathogens and bacterial biofilm formation. The antioxidant from Arthrinium sp. 10 KUC21332 was separated by bioassay-guided isolation and identified to be gentisyl alcohol, and the antioxidant of Arthrinium saccharicola KUC21221 was identical. These results demonstrate that many unexploited Arthrinium species still exist in marine environments and that they are a great source of bioactive compounds.

SUBMITTER: Heo YM

PROVIDER: S-EPMC6315899 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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Diversity and Ecology of Marine Algicolous Arthrinium Species as a Source of Bioactive Natural Products.

Heo Young Mok YM Kim Kyeongwon K Ryu Seung Mok SM Kwon Sun Lul SL Park Min Young MY Kang Ji Eun JE Hong Joo-Hyun JH Lim Young Woon YW Kim Changmu C Kim Beom Seok BS Lee Dongho D Kim Jae-Jin JJ

Marine drugs 20181214 12

In our previous study, all Arthrinium isolates from Sargassum sp. showed high bioactivities, but studies on marine <i>Arthrinium</i> spp. are insufficient. In this study, a phylogenetic analysis of 28 Arthrinium isolates from seaweeds and egg masses of Arctoscopus japonicus was conducted using internal transcribed spacers, nuclear large subunit rDNA, β-tubulin, and translation elongation factor region sequences, and their bioactivities were investigated. They were analyzed as 15 species, and 11 ...[more]

PMID: 30558255

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Dataset Information

Diversity and Ecology of Marine Algicolous Arthrinium Species as a Source of Bioactive Natural Products.

Publications

Diversity and Ecology of Marine Algicolous Arthrinium Species as a Source of Bioactive Natural Products.

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