Dual-Family Peptidylprolyl Isomerases (Immunophilins) of Select Monocellular Organisms.
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ABSTRACT:
SUBMITTER: Barik S
PROVIDER: S-EPMC6316441 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Dual-Family Peptidylprolyl Isomerases (Immunophilins) of Select Monocellular Organisms.
Biomolecules 20181115 4
The dual-family peptidylprolyl <i>cis-trans</i> isomerases (immunophilins) represent a naturally occurring chimera of the classical FK506-binding protein (FKBP) and cyclophilin (CYN), connected by a flexible linker. They are found exclusively in monocellular organisms. The modular builds of these molecules represent two distinct types: CYN-(linker)-FKBP and FKBP-3TPR (tetratricopeptide repeat)-CYN. Abbreviated respectively as CFBP and FCBP, the two classes also exhibit distinct organism preferen ...[more]
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