Ontology highlight
ABSTRACT:
SUBMITTER: Shaikh SR
PROVIDER: S-EPMC6319960 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Shaikh Saame Raza SR Shaver Patti R PR Shewchuk Brian M BM
Molecular nutrition & food research 20180528 13
<h4>Scope</h4>Dietary fat composition can modulate gene expression in peripheral tissues in obesity. Observations of the dysregulation of growth hormone (GH) in obesity indicate that these effects extend to the hypothalamic-pituitary (H-P) axis. The authors thus determine whether specific high fat (HF) diets influence the levels of Gh and other key gene transcripts in the H-P axis.<h4>Methods and results</h4>C57BL/6 mice are fed a lean control diet or a HF diet in the absence or presence of OA, ...[more]