Ontology highlight
ABSTRACT:
SUBMITTER: Porcu C
PROVIDER: S-EPMC6321282 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20181208 12
Oleuropein (Ole) is one of the most plentiful phenolic compounds with antioxidant, anti-inflammatory, anti-atherogenic, hypoglycemic and hypolipidemic effects. The aim of our study was to establish whether the positive Ole-related effects on liver steatosis could be associated with autophagy. Female and male C57BL/6J mice were fed normal diet (ND) or high-fat diet (HFD) for eight weeks, and Ole was added or not for the following eight weeks. The autophagy-related proteins Akt, mTOR, AMPK, ULK1, ...[more]