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Salvia elegans, Salvia greggii and Salvia officinalis Decoctions: Antioxidant Activities and Inhibition of Carbohydrate and Lipid Metabolic Enzymes.


ABSTRACT: Salvia elegans Vahl., Salvia greggii A. Gray, and Salvia officinalis L. decoctions were investigated for their health-benefit properties, in particular with respect to antioxidant activity and inhibitory ability towards key enzymes with impact in diabetes and obesity (?-glucosidase, ?-amylase and pancreatic lipase). Additionally, the phenolic profiles of the three decoctions were determined and correlated with the beneficial properties. The S. elegans decoction was the most promising in regard to the antioxidant effects, namely in the scavenging capacity of the free radicals DPPH, NO and O?•?, and the ability to reduce Fe3+, as well as the most effective inhibitor of ?-glucosidase (EC50 = 36.0 ± 2.7 ?g/mL vs. EC50 = 345.3 ± 6.4 ?g/mL and 71.2 ± 5.0 ?g/mL for S. greggii and S. officinalis, respectively). This superior activity of the S. elegans decoction over those of S. greggii and S. officinalis was, overall, highly correlated with its richness in caffeic acid and derivatives. In turn, the S. officinalis decoction exhibited good inhibitory capacity against xanthine oxidase activity, a fact that could be associated with its high content of flavones, in particular the glycosidic forms of apigenin, scutellarein and luteolin.

SUBMITTER: Pereira OR 

PROVIDER: S-EPMC6321363 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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<i>Salvia elegans</i>, <i>Salvia greggii</i> and <i>Salvia officinalis</i> Decoctions: Antioxidant Activities and Inhibition of Carbohydrate and Lipid Metabolic Enzymes.

Pereira Olívia R OR   Pereira Olívia R OR   Catarino Marcelo D MD   Afonso Andrea F AF   Silva Artur M S AMS   Cardoso Susana M SM  

Molecules (Basel, Switzerland) 20181201 12


<i>Salvia elegans</i> Vahl., <i>Salvia greggii</i> A. Gray, and <i>Salvia officinalis</i> L. decoctions were investigated for their health-benefit properties, in particular with respect to antioxidant activity and inhibitory ability towards key enzymes with impact in diabetes and obesity (α-glucosidase, α-amylase and pancreatic lipase). Additionally, the phenolic profiles of the three decoctions were determined and correlated with the beneficial properties. The <i>S. elegans</i> decoction was th  ...[more]

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