Ontology highlight
ABSTRACT:
SUBMITTER: Del Pinto R
PROVIDER: S-EPMC6321367 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Del Pinto Rita R Ferri Claudio C
International journal of molecular sciences 20181122 12
Low-grade chronic inflammation is a common denominator in atherogenesis and related diseases. Solid evidence supports the occurrence of an impairment in the innate and adaptive immune system with senescence, favoring the development of acute and chronic age-related diseases. Cardiovascular (CV) diseases (CVD), in particular, are a leading cause of death even at older ages. Inflammation-associated mechanisms that contribute to CVD development include dysregulated redox and metabolic pathways, gen ...[more]