Ontology highlight
ABSTRACT:
SUBMITTER: Pitchford LM
PROVIDER: S-EPMC6321651 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Pitchford Lisa M LM Rathmacher John A JA Fuller John C JC Daniels J Scott JS Morrison Ryan D RD Akers Wendall S WS Abumrad Naji N NN Amarnath Venkataraman V Currey Patricia M PM Roberts L Jackson LJ Oates John A JA Boutaud Olivier O
BMC pharmacology & toxicology 20190105 1
<h4>Background</h4>2-Hydroxybenzylamine (2-HOBA) is a selective scavenger of dicarbonyl electrophiles that protects proteins and lipids from being modified by these electrophiles. It is currently being developed for use as a nutritional supplement to help maintain good health and protect against the development of conditions associated with dicarbonyl electrophile formation, such as the cognitive decline associated with Mild Cognitive Impairment and Alzheimer's disease.<h4>Methods</h4>In this fi ...[more]