Ontology highlight
ABSTRACT:
SUBMITTER: Goswami M
PROVIDER: S-EPMC6321986 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Goswami Meghali M Hourigan Christopher S CS
Current drug targets 20170101 3
Acute myeloid leukemia (AML) was the first malignancy for which immunotherapy, in the form of allogeneic hematopoietic stem cell transplantation (allo-HSCT), was integrated into the standard of care. Allo-HSCT however is an imperfect therapy associated with significant morbidity and mortality while offering only incomplete prevention of AML clinical relapse. These limitations have motivated the search for AML-related antigens that might be used as more specific and effective targets of immunothe ...[more]