Randomized prospective phase III trial of 68Ga-PSMA-11 PET/CT molecular imaging for prostate cancer salvage radiotherapy planning [PSMA-SRT].
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ABSTRACT:
SUBMITTER: Calais J
PROVIDER: S-EPMC6322287 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
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Randomized prospective phase III trial of <sup>68</sup>Ga-PSMA-11 PET/CT molecular imaging for prostate cancer salvage radiotherapy planning [PSMA-SRT].
Calais Jeremie J Czernin Johannes J Fendler Wolfgang P WP Elashoff David D Nickols Nicholas G NG
BMC cancer 20190107 1
<h4>Background</h4>Salvage radiotherapy (SRT) for prostate cancer (PCa) recurrence after prostatectomy offers long-term biochemical control in about 50-60% of patients. SRT is commonly initiated in patients with serum PSA levels < 1 ng/mL, a threshold at which standard-of-care imaging is insensitive for detecting recurrence. As such, SRT target volumes are usually drawn in the absence of radiographically visible disease. <sup>68</sup>Ga-PSMA-11 (PSMA) PET/CT molecular imaging is highly sensitive ...[more]
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